What medication should the nurse check for in a client experiencing delirium?

In the context of a client experiencing delirium, it is essential to consider the effects of the medications they are taking. Diphenhydramine HCL, commonly known as Benadryl, is an antihistamine that can have sedative effects and may lead to confusion, altered mental status, and delirium, especially in older adults or those with compromised cognitive function. Anticholinergic medications like diphenhydramine can exacerbate cognitive issues, making it critical for the nurse to assess for its presence in a patient's medication regimen.

Other medications listed generally do not have the same impact on cognition. Prednisone, a corticosteroid, might influence mood and mental status but is not a direct cause of delirium. Atorvastatin, a cholesterol-lowering medication, primarily affects lipid levels without significant direct effects on mental status. Lisinopril, an antihypertensive, is also not associated with delirium. Therefore, monitoring for diphenhydramine is crucial in managing and preventing exacerbation of delirium in affected clients.